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344,345 Similarly, IOX1, an inhibitor of -KG oxygenases and a potent inhibitor of lysine demethylase 3 A (KDM3A) and KDM4A, has been found to reduce TET enzymatic activities in helper T cells, emerging as a potential epigenetic drug for various autoimmune diseases
doi:10.1056/NEJMoa2215025 Jaiswal V, Sawhney A, Nebuwa C, et al
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