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Three 30-day iHLOs of similar sizes (40 L/well) were transferred to a 384-well ultra-low attachment plate (Corning, catalog: 4516) and incubated for 24 h before testing

Unlike semaglutide, which is given weekly, liraglutide requires a daily injection

In addition to keeping blood and nerve cells healthy, it contributes to the effective functioning of several critical bodily processes, including energy metabolism

Once phosphorylated the tyrosine residues of the beta subunit serve as docking sites for downstream signaling mediators including extracellular signal-regulated kinase (ERK) and the phosphatidylinositol-3-kinase (P13K) pathway [78] ( Figure 2 )