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Moreover, NMN administration can significantly elevate NAD + biosynthesis in white adipose tissue, heart and the liver, but not the NAD + content in brown adipose tissue and kidney, suggesting a tissue- and cell-type-specific transportation of NMN to cells or tissues for NAD + biosynthesis presumably due to the deferent expression pattern of NRK1

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NsPCS were dissolved in Milli-Q water and adjusted to a concentration of 220 mg/L