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Cognitive Health and Neurological Protection NAC crosses the blood-brain barrier, reduces glutamate excitotoxicity, promotes neurogenesis, and counters oxidative stress in neurons

This is consistent with microarray studies that demonstrated significantly high expression of TGFBI in methotrexate, cisplatin, doxorubicin, vincristine, topotecan and paclitaxel-resistant ovarian cancer cell lines and reconciled those findings to changes in ECM remodeling in response to drug treatment [47]

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