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The transfer and stable integration of the HSV thymidine kinase gene into mouse cells

10.1002/path.2277 153 XueX

In the pancreatic cancer tissue, the tumor-associated fibroblast (TAF) continuously produces IGF-1, which stimulates pancreatic islet beta cells to proliferate and secrete more insulin through a bidirectional microcirculation system in the pancreas (Dheen et al., 1996

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