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Description
Neuroprotective agents are drugs that halt the ischemic cascade, prevent secondary injury, or decrease the loss of vulnerable neurons in the ischemic penumbra [56]

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The mechanism comprises a sequence of reactions with first 1acyl-DHAP binding to AGPS, then reaction of acyl-DHAP with the cofactor flavin adenine dinucleotide (FAD) for release of a fatty acid containing both oxygen atoms from the ester linkage in acyl-DHAP, binding of the fatty alcohol to AGPS, and finally formation of 1alkyldihydroxyacetone phosphate (1alkyl-DHAP)

Combining L-carnitine with a stimulant-containing fat burner is mechanistically plausible but not well tested in head-to-head combination trials