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Similar content being viewed by others Main PTX has been an influential and powerful chemotherapeutic drug for treating diverse cancers including breast, pancreatic, ovarian, Kaposis sarcoma, esophageal, cervical and non-small-cell lung cancers 1,2

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The drop in inner membrane potential is accompanied by mitochondrial morphological changes of tubular mitochondria into biconcave discoid structures, which are initially reversible ( Figure 18 )
