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The no-DAC version produces pulsatile GH release
Nat Chem Biol (2013) 9(5):3006
This may suggest that Parasutterella changes are linked to the diet switch or the series of diets the animals have experienced in their lifetime
For adults over 65, no dose adjustment is required, but careful monitoring for adverse effects is prudent as older adults often have multiple comorbidities and medications that increase complication risk
