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Observational cohort studies of patients with AD and a various follow-up ranging from 10 months to over 10 years, reported a slower [61, 66,67,68] or similar [69] cognitive decline in statins users compared to non-users

Similarly, branched-chain amino acids, such as leucine, isoleucine, and valine, are catabolized in skeletal muscle to produce acetyl-CoA and succinyl-CoA, which enter the TCA cycle and contribute to ATP production

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