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CBS is a 63 kDa heme containing enzyme that forms a homotetramer and catalyzes the condensation of homocysteine with serine to form cystathionine (Fig
doi: 10.1016/j.neuroscience.2004.07.012
Nevertheless, dysregulation of HIF-1 signaling axis would lead to skeletal dysplasia by interfering with cellular bioenergetics and biosynthesis (Stegen et al., 2019)
The wanderings of a free radical
