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Ex Vivo Skin Permeation Test of GSH-HA MN Patches To estimate the onset as well as the duration of GSH release from GSH 2.5 -HA MNs, the Franz cell study was performed for 48 h by placing the skin of a SD rat under simulated physiological conditions (Figure 6)

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Obesity and insulin resistance are associated with adipose tissue remodeling, characterized by increases in macrophages (discussed further in the section on anti-inflammatory and diabetogenic actions of GCs), fibrosis, and the extracellular matrix

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PC also plays an important role in supporting normal liver function and in helping protect the liver from alcohol, pollutants, viruses, and other toxic agents

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1 (Gaussian Inc, Wallingford, 2009), pp

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