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The administration of 1200 mg oral lipoic acid daily for 24 months seems to protect the wholebrain volume of patients, whereas the decline in walking speed was not alleviated [188]

Cell cultures with human cells show variable effects of Zn on cytokines depending on its concentration and cell status (105, 106)

Forder A, Zhuang R, Souza VGP et al (2023) Mechanisms contributing to the comorbidity of COPD and lung cancer

This effect is generated through hyperactivation of the inflammasome, resulting in increased IL-1 secretion and CNS inflammation