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MOTS-c Research & Scientific Overview Jump to: Structure | Mechanism | Studies | Pharmacokinetics | Protocols | Limitations | Lead Researcher | References MOTS-c Molecular Structure & Chemical Properties MOTS-c peptide represents a paradigm-shifting discovery in mitochondrial biology, being the first mitochondrial-encoded peptide shown to directly regulate nuclear gene expression in response to metabolic stress

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S2a, b, green), consisting of helices 49 (residues 76197), displayed the highest stability with a RMSD around ~24 in both structures in the last 5 s

Increases in [cAMP] i are well controlled by phosphodiesterases [13]