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Currently, 5-Amino-1MQ is being investigated for its potential role in studies involving metabolic health, adiposity regulation, weight management models, and insulin sensitivity pathways

IGF-binding protein-2 protects against the development of obesity and insulin resistance

It promotes lipolysis, the biological process that breaks down fat cells stored triglycerides into free fatty acids and glycerol for utilization as fuel (2)

Current treatment options include approved drugs such as serotonin-norepinephrine reuptake inhibitors, e.g., duloxetine, gabapentinoids such as pregabalin and gabapentin, topical treatment with capsaicin, and several off-label use drugs such as other antidepressants (e.g., tricyclic antidepressants), antiepileptic drugs, and weak and strong opioids