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Even if caloric intake remains similar, the metabolic effects can drive additional fat loss compared to GLP-1 only approaches

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focused specifically on measuring putative notochordal and NP cell markers and found expression levels of previously identified novel NP and notochordal markers such as KRT8 , KRT18 , KRT19 , CA12 , FOXA2 , and NOG stayed consistent regardless of donor age or degeneration (Richardson et al., 2017)