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Notably, histological analysis at this time point revealed no significant hepatocyte damage, suggesting that the rapid decrease in hepsin protein levels may primarily result from the activation and subsequent degradation of the hepsin serine protease in response to APAP-induced hepatotoxicity

The balance between mitochondrial division and fusion is an important basis for normal cellular activity and the maintenance of energy homeostasis, as well as for neurons to perform normal functions (Mishra and Chan, 2016)

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