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Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets

doi: 10.1002/phy2.153 97

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Together with peroxiredoxins (PRXs) and thioredoxins (TRXs), the ascorbateglutathione cycle regulates ROS accumulation in each compartment, with perhaps the exception of the apoplast/cell wall compartment (Foyer and Hanke, 2022)