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Here we unveiled an essential role of E3 ligase SMAD ubiquitylation regulatory factor 1 (Smurf1)-mediated phosphoinositide-dependent protein kinase 1 (PDK1) neddylation in PI3KAkt signaling and tumorigenesis

, Hayashi Y., and Hell J

J Cancer Res Clin Oncol (2008) 134(5):5519

Treatment of men with erectile dysfunction with transurethral alprostadil
