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Several small-molecule compounds could play a good therapeutic effect by acting on NF-B signaling pathway to mediate autophagy [181]

Mutations in FUS, TDP-43, SOD1, and C9ORF72 increase DNA damage, alter mitochondria fusion and fission, alter calcium homeostasis, and reduce the activity of respiratory chain complexes II and IV (Kodavati et al., 2020

Drug Resist Updat 2016

New therapies and insights into the changing landscape of colorectal cancer
