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Targeting TPC2 sensitizes acute lymphoblastic leukemia cells to chemotherapeutics by impairing lysosomal function

Although the enduring symbiotic relations between the nucleus and the mitochondrion remain largely unexplored in cancer, they may provide us with a better understanding of cancer

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Further, clinical studies were performed which showed that IN administration and systemic delivery of cardiovascular drugs are suitable alternatives because they result in a more rapid onset of action compared with the commonly parenteral administered formulations [121, 122]
