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E2 increased TH promoter activity and expression in the locus coeruleus of female mice but decreased them in males [105]

Preclinical studies have explored its involvement in repair processes, vascular adaptation, and inflammatory regulation, positioning it as a molecule of interest in musculoskeletal and gastrointestinal research contexts (1)

Kurihara Y, Kanki T, Aoki Y, Hirota Y, Saigusa T, Uchiumi T, Kang D

Results from our work will provide a biological understanding of the cell and molecular basis of human life and child health, and potentially the foundation for a cell based therapy to overcome human infertility