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However, favoring the theory of hyperhomocysteinemia-induced platelet activation, in vitro studies have proposed that, besides its direct cytotoxicity that damages endothelial cells (Dudman et al, 1991

Antioxidant: GHK-Cu activates the body's own antioxidant systems (SOD, catalase), rather than just scavenging free radicals directly

Bmj 370, m2687

Given the diverse roles these molecules play in cellular metabolismranging from antioxidant defense to nucleotide biosynthesiscells must carefully modulate the activity of the PPP to meet their varying metabolic demands
