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Frontiers in aging neuroscience
Furthermore, analyses using RHLs and tof11 mutants revealed that TOF11 is the causal gene underlying qAAD11_1 (Fig
On the other hand, glutathione-mimetic compounds or -glutamylcysteine (-GC), the limiting substrate for GSH biosynthesis, ameliorate brain pathologies and memory deficits in APP/PS1 63,64
Aging is directly related to the damage caused by free radicals, particularly ROS causing oxidative stress (Sies, 2015
