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Shah JAMA Internal Medicine.2026
To further investigate this phenomenon, the expression of key genes and pathways involved in ferroptosis was analyzed in the livers of mice with iron overload, with or without theaflavins treatment
Iron typically binds to transferrin (TF) in a Fe 3+ form, thereby entering cells via transferrin receptor (TFRC) [43], then get reduced to Fe 2+ by Six-Transmembrane Epithelial Antigen of Prostate (STEAP3) metal reductase in endosome
