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Piya S, McQueen T, Mak D, Konopleva M, Zweidler-McKay P, Lu J, Qian Y, Andreeff M , Borthakur G

The exact mechanisms are complex, but broadly NAD+ injections may counteract NAD+ depletion and support better cellular function, especially in high-demand tissues like the brain and muscles

Under normal conditions, the ROS generated in the mitochondria are effectively neutralized by the cells antioxidant defense systems [67,68,87]

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