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The rostral two burr holes were placed just basally from the posterior interocular line, the basal two burr holes were placed just rostral to the lambdoid suture (and transverse sinuses) on both sides, and the middle two burr holes were placed in the line between the basal and rostral burr holes

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Essentially the injection may be a temporary measure to fix levels

When an intensive diet and exercise regime was incorporated into the study design, the peptides weight loss signal essentially disappeared versus the control group