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The ACSL4 (acyl-CoA synthetase long-chain family member 4) was identified as an essential component for the execution of ferroptosis by two independent screening approaches: microarray analysis of ferroptosis-resistant cell lines and a genome-scale CRISPR-guided genetic screen

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Analytical Sciences 2025 , 41 (10) , 1637-1645
Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations
