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As opposed to the groups without laser irradiation, the C@PA(+) and SeC@PA(+) groups could significantly reduce GSH levels in the biofilms by producing NO after laser irradiation, and GSH levels in SeC@PA(+) group was lower than that in the C@PA(+) group

Survival advantage associated with metformin usage in patients with colorectal cancer (CRC) and type II noninsulin-dependent diabetes (NIDDM) 29, 2011
References: Mancini E, Beglinger C, Drewe J, Zanchi D, Lang UE, Borgwardt S

These thresholds were chosen to balance biological relevance, statistical significance, and clinical translational feasibility
