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Thus, beyond its roles in immunity and bone metabolism, HIF-1 supports local tissue repair through VEGF-mediated angiogenesis

You might consider using different serums on different areas (e.g., a hydrating serum on dry patches and a purifying serum on oily zones)

Wong BX, Tsatsanis A, Lim LQ et al (2014b) -Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin

An imbalance in favor of antioxidants can lead to so-called antioxidative stress, which may also have harmful effects, particularly when synthetic antioxidants are consumed in excessive amounts [165]