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In vivo , adding hydroxycitrate (250 mg/kg) and LA (10 mg/kg) to cisplatin or methotrexate was more effective against tumour development than individual chemotherapeutic drugs or the combination of lipoic acid and hydroxycitrate administered [106]
M.HashimotoA
However, at the same time there are abundant reports of harmful effects such as oxidative stress, DNA damage, protein modification and lysis of stromal cells (Mustafa et al., 2017[11])
Torrente L, DeNicola GM
