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However, studies using small molecule NO donors (N-diazeniumdiolate, S-nitrosothiol, etc) have yet to meet clinical requirements due to the short half-life and initial burst-release profile of NO donors
doi: 10.1038/nature04791
Does the formulation change a validated local biomarker or clinical outcome
J Clin Oncol 28:44854491 Wilson P, Anastasaki A, Owen MR, Kempe K, Haddleton DM, Mann SK, Johnston AP, Quinn JF, Whittaker MR et al (2015) Organic arsenicals as efficient and highly specific linkers for protein/peptidepolymer conjugation
