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This correlation provides the most direct evidence for the core protective role of GPX4 in OA

e.g., miR-148a modulates DNMT1 under hypoxia ( Chromatin remodeler ARID1A, critical for endometrial receptivity, is downregulated in eutopic endometrium of women with endometriosis, likely via epigenetic/transcriptional mechanisms rather than mutations

25,34 Medical treatment For patients who have symptoms of liver involvement, and have biochemical evidence of cholestasis or who are at high risk for developing hepatic complications, pharmacological therapy should be considered

Klein BE, Klein R, Lee KE, Meuer SM
