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Interestingly, Venetoclax-resistant MOLM-13 cells were more sensitive to the MCL-1 inhibitor AZD-5991 compared to parental cells, while being highly resistant to Venetoclax and AZD-4320 (Supplementary Fig

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E In the first, the lymphocyte develops this capacity to proliferate and only when it is 11 days post F We must therefore postulate a period during which the lymphocytes are being molded to tolerate self-components or more simply being killed off if they do not

Where available, the intravenous loading dose is 150 mg/kg by intravenous infusion in 200 mL of 5% dextrose over 60 minutes, followed by 50 mg/kg by intravenous infusion in 500 mL of 5% dextrose over 4 hours, then 100 mg/kg by intravenous infusion in 1000 mL of 5% dextrose over 16 hours