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But the effect size is modest and conditional

A: Yes, it is recommended to consult with your healthcare provider before starting any new dietary supplement, especially if you have pre-existing medical conditions, are pregnant or breastfeeding, or are taking other medications
This finding raises the possibility that patients with RLS may have compromised supraspinal dopaminergic control over the muscle (Yeh et al., 2016)

In these situations an oral supplement may be inadequate or too slow, so clinicians rely on intravenous or intramuscular levocarnitine
