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A study in more than 5000 women indicates that including folic acid (2.5 mg/day), B6 (50 mg/day) and B12 (1 mg/day) in the diet may prevent and reduce the risk of AMD (Christen 2009)

Additionally, the loss of GlS1 leads to -kG deficiency, and impairs the differentiation of Th17 cells [84].Glutamine uptake transporters such as ASCT2, Solute carrier family 7, member 5 (SLC7A5) and Sodium-coupled Neutral Amino Acid Transporter (SNAT), when blocked, inhibit the differentiation of CD4 + Th1 and Th17 cells [83], while SLC7A5-mediated glutamine uptake regulates the activation of c-MYC-dependent Teff cells