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Fe 3+ is known to stimulate free radical formation particularly converting H 2 O 2 to highly reactive and toxic OH - through Fenton reaction, in which the presence of either compounds are malicious and a threat to initiate oxidative damage as stressed in the earlier section of the review [216]

It has been demonstrated that ROS primarily stem from the electron transport chain (ETC) complex within mitochondria

& Burgoyne, R
