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The result of this study showed that lupus PBLs have increased oxygen consumption through mitochondrial ETC complex I, which is the main source of oxidative stress in SLE, and this complex is inhibited by NAC [22]

The use of ascorbic acid, vitamin C in excess of the recommended dietary allowance during normal pregnancy should be avoided unless, in the judgment of the physician, potential benefits in a specific, unique case outweigh the significant hazards involved (1)

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