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noted that although large sample sizes are typically required for Mendelian randomization studies, it is not always necessary to measure risk factors for all participants in the study, and thus, sample size is not the sole criterion for evaluating MR analysis 26

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Keywords: abiotic stress, reactive oxygen species (ROS), hydrogen peroxide (H 2 O 2 ), catalase (CAT), ascorbate peroxidase (APX) 1

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