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EGCGs interaction with cellular pathways is crucial in HD treatment, as it activates AMPK signaling, which plays a vital role in cellular energy homeostasis and autophagy regulation

However, considering melatonins thoroughly investigated anti-inflammatory actions in other tissues, it is expected that melatonin would suppress inflammatory responses in RPE cells as in other tissues

The treatment process 1In-depth medical assessment and goal setting 2Personalised NAD+ dose and protocol planning 3Slow drip infusion over 24 hours in a comfortable suite 4Post-infusion review and ongoing protocol adjustments None

Lancet Public Health 5 , e196e203 (2020)
