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Thus treatment with L-carnitine enables CPT I to transfer the acyl groups from acyl-CoAs to free carnitine, yielding acylcarnitine esters, which prevents the accumulation of, and subsequent damage from, high levels of acyl-CoAs [19]

Oxidative stress is a physiological condition in the system where the outputs of reactive oxygen species (ROS) tends to alter the vigor of antioxidant systems at either the cellular or system level ( Increased level of oxidative products like thiobarbituric acid reactive substances and Malondialdehyde ( Endogenous antioxidant enzymes SOD and CAT that make up the antioxidant cellular enzymatic system, function as the first line of defense and are important indicators of the oxidation status of animal tissues ( 2 ) into hydrogen peroxide (H 2 0 2 ) and an oxygen molecule (O 2 ) to reduce the damage caused by the former

First, it includes an underrepresented South Asian pediatric population, contributing region-specific data to the ASD metabolomics literature