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Description
Tumors require blood supply to grow beyond a certain size, and they hijack angiogenic pathways to build their own vascular networks
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For tesofensine, missing a single daily dose has minimal impact given the eight-day half-life, but missing multiple consecutive doses (3 days) may cause rebound appetite and require re-initiation at a lower dose to avoid side effects from rapid plasma level changes
Various administration routes seem feasible : Intraarticular, intravesical, and intravenous administration were all tolerated without apparent issues
