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O.ChengQ.MundeE
Amongst ~150 previously unreported mutations that affected WNT signaling, we discovered gain-of-function and separation-of-function alleles that reveal mechanisms of complex assembly, including a -catenin region regulating TCF/LEF transcription factor binding
A Phase III randomized controlled trial in Asian populations confirmed the efficacy of UPA in treating menorrhagia, demonstrating comparable results to leuprolide
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