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Poor posture, prolonged jaw clenching, and misalignment of the teeth are among the reasons, as are fractures and diseases like lockjaw, in which the muscles around the jaw spasm and limit the opening of the mouth

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(Figures 12A, B)

In most animal experiments, AS model mice exhibit a significant reduction in GM diversity, an increase in the relative abundance of Turicibacter , Desulfovibrio , Lactococcus , Enterococcus , and an decrease in the relative abundance of Bacteroides , Roseburia , Lactobacillus , and Alloprevotella [51,52,53,54,55,56]
