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In the nine-quadrant analysis, quadrant Q3 (concordant upregulation) contained only three genes, all belonging to the selenoprotein family: SELENOW , SELENOP , and GPX1

The most common cause of CO-GHD is idiopathic and can be isolated or associated with other pituitary hormone deficiencies, while AO-GHD is frequently acquired from hypothalamic-pituitary tumors and/or secondary to their treatment (82)

doi: 10.1038/s41467-025-57152-7 237 LiY.et al

(d) NADP + , Cd accumulation, ABA, DHA, DW, AsA, and MDA were closely associated with each other
