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Since cisplatin cytotoxicity is mainly due to its ability to cause DNA damage, DNA repair capacity is expected to be one of most important, and therefore studied cisplatin-resistance mechanisms
It is clear that these dual tags did not negatively impact the protein activity (fluorescence) or binding capability to GSH
Fe3+ binds to transferrin receptors on the cell membrane and enters the cell
[PUBMED Abstract] Gajjar A, Harrison PL, Sandlund JT, et al.: Traumatic lumbar puncture at diagnosis adversely affects outcome in childhood acute lymphoblastic leukemia
