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Description
Among the more potent compounds were the racemic pyridine derivative 37 (HFI-419), and the quinoline derivatives 38 (HFI-435) and 39 (HFI-437) exhibiting K i values of 420, 360, and 20 nM, respectively (Figure 9)

Jan 1996;45(1):12-23

La grande maggioranza dei dati proviene da studi in vivo condotti su modelli murini e di ratto, nonch da esperimenti in vitro su colture cellulari

We choose to use time as a predictor for two main reasons