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Causing throbbing head pain and accompanied by symptoms such as nausea, light sensitivity and blurred vision, a migraine is conventionally treated through oral medication, either to curb the severity of symptoms during an attack or to prevent future migraine attacks

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[99] A person with cobalamin C disease, a rare autosomal, recessive, inheritance disease which results in combined methylmalonic aciduria and homocystinuria), [100] can be treated with intravenous or intramuscular hydroxocobalamin

Flint's drinking water became contaminated with lead in April 2014 while the city was under the control of a state-appointed emergency manager
