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pain was assessed by VAS and pain-related quality-of-life (QoL) scores

While there is no scientific evidence recommending against taking B12 at night, because of its role in energy production, it can elicit a stimulatory effect in some people, as do the other B vitamins

These investigators found that untreated Cushings disease patients had low GH and high IGF-I levels without clinical features of acromegaly, and after surgery with disease remission, serum IGF-I levels normalized

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