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Patients were identified by chart review and were divided into two subgroups: early-therapy (begun within 12 months, mean 3 months, of starting insulin) and late therapy (begun more than 12 months, mean 168 months, after starting insulin)

This resulted in about half of the SNPs for each trait being associated with a gene, which is a useful number of genes for GO-term enrichment analysis

When enough heat (activation energy) is applied, one of the unpaired electrons flips to form an electron pair, which then participates in the combustion reaction

Differential roles of Sirt1 in HIF-1alpha and HIF-2alpha mediated hypoxic responses