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Description
Activated IGF-1R phosphorylates insulin receptor substrate proteins (IRS-1 and IRS-2), which recruit and activate PI3K
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Dosing typically starts very low and increases over time (titration), a strategy often used when comparing Semaglutide vs tirzepatide
Nrf2 Activation: In response to oxidative stress, Nrf2 activates the transcription of genes involved in antioxidant defense, including those involved in the synthesis of glutathione
